Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors

CONTEXT: Aromatase deficiency causes obesity and insulin resistance in aromatase knockout mice and humans with rare mutations of the aromatase gene (CYP19). Aromatase inhibitors are a commonly prescribed therapy for postmenopausal breast cancer. OBJECTIVE: We hypothesized that aromatase inhibitors i...

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Veröffentlicht in:J Clin Endocrinol Metab
Hauptverfasser: Gibb, Fraser W, Dixon, J Michael, Clarke, Catriona, Homer, Natalie Z, Faqehi, Abdullah M M, Andrew, Ruth, Walker, Brian R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Clinical Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642666/
https://ncbi.nlm.nih.gov/pubmed/30920624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02339
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