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Long noncoding RNA EMS connects c-Myc to cell cycle control and tumorigenesis

Deregulated expression of c-Myc is an important molecular hallmark of cancer. The oncogenic function of c-Myc has been largely attributed to its intrinsic nature as a master transcription factor. Here, we report the long noncoding RNA (lncRNA) E2F1 messenger RNA (mRNA) stabilizing factor (EMS) as a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Chenfeng, Yang, Yang, Zhang, Guang, Li, Jingxin, Wu, Xianning, Ma, Xiaoling, Shan, Ge, Mei, Yide
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642410/
https://ncbi.nlm.nih.gov/pubmed/31262817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903432116
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