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Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

Light-sensitive G protein-coupled receptors (GPCRs)—rhodopsins—absorb photons to isomerize their covalently bound retinal, triggering conformational changes that result in downstream signaling cascades. Monostable rhodopsins release retinal upon isomerization as opposed to the retinal in bistable rh...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Varma, Niranjan, Mutt, Eshita, Mühle, Jonas, Panneels, Valérie, Terakita, Akihisa, Deupi, Xavier, Nogly, Przemyslaw, Schertler, Gebhard F. X., Lesca, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642406/
https://ncbi.nlm.nih.gov/pubmed/31249143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902192116
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