Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs

Tandem repeat proteins exhibit native designability and represent potentially useful scaffolds for the construction of synthetic biomimetic assemblies. We have designed 2 synthetic peptides, HEAT_R1 and LRV_M3Δ1, based on the consensus sequences of single repeats of thermophilic HEAT (PBS_HEAT) and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hughes, Spencer A., Wang, Fengbin, Wang, Shengyuan, Kreutzberger, Mark A. B., Osinski, Tomasz, Orlova, Albina, Wall, Joseph S., Zuo, Xiaobing, Egelman, Edward H., Conticello, Vincent P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642399/
https://ncbi.nlm.nih.gov/pubmed/31262809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903910116
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