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Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy

Selective autophagy recycles damaged organelles and clears intracellular pathogens to prevent their aberrant accumulation. How ULK1 kinase is targeted and activated during selective autophagic events remains to be elucidated. In this study, we used chemically inducible dimerization (CID) assays in t...

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Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Vargas, Jose Norberto S., Wang, Chunxin, Bunker, Eric, Hao, Ling, Maric, Dragan, Schiavo, Giampietro, Randow, Felix, Youle, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642318/
https://ncbi.nlm.nih.gov/pubmed/30853401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.010
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