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Comparison of droplet digital PCR and direct Sanger sequencing for the detection of the BRAF (V600E) mutation in papillary thyroid carcinoma

BACKGROUND: The BRAF (V600E) mutation status is a useful diagnostic and prognostic marker for papillary thyroid carcinoma (PTC). Although it is a commonly used method, Sanger sequencing has several limitations in detecting the BRAF (V600E) mutation. The aim of this study was to evaluate the efficien...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Wang, Zhuo, Sun, Kejing, Jing, Changwen, Cao, Haixia, Ma, Rong, Wu, Jianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642310/
https://ncbi.nlm.nih.gov/pubmed/31021028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22902
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