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Consequences of Y chromosome microdeletions beyond male infertility

PURPOSE: The human Y chromosome plays a central role in sex determination and spermatogenesis. The azoospermia factor (AZF) loci on the Y chromosome contain genes that were thought to be testis specific with their deletions leading to spermatogenic failure. However, beyond the testis, the AZF genes...

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Détails bibliographiques
Publié dans:J Assist Reprod Genet
Auteurs principaux: Colaco, Stacy, Modi, Deepak
Format: Artigo
Langue:Inglês
Publié: Springer US 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642242/
https://ncbi.nlm.nih.gov/pubmed/31214882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01492-z
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