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Two types of functionally distinct Ca(2+) stores in hippocampal neurons

It is widely assumed that inositol trisphosphate (IP(3)) and ryanodine (Ry) receptors share the same Ca(2+) pool in central mammalian neurons. We now demonstrate that in hippocampal CA1 pyramidal neurons IP(3)- and Ry-receptors are associated with two functionally distinct intracellular Ca(2+) store...

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Publicat a:Nat Commun
Autors principals: Chen-Engerer, Hsing-Jung, Hartmann, Jana, Karl, Rosa Maria, Yang, Jun, Feske, Stefan, Konnerth, Arthur
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642203/
https://ncbi.nlm.nih.gov/pubmed/31324793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11207-8
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