Mutagenesis separates ATPase and thioesterase activities of the peroxisomal ABC transporter, Comatose

The peroxisomal ABC transporter, Comatose (CTS), a full length transporter from Arabidopsis has intrinsic acyl-CoA thioesterase (ACOT) activity, important for physiological function. We used molecular modelling, mutagenesis and biochemical analysis to identify amino acid residues important for ACOT...

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發表在:Sci Rep
Main Authors: Carrier, David J., van Roermund, Carlo W. T., Schaedler, Theresia A., Rong, Hong Lin, IJlst, Lodewijk, Wanders, Ronald J. A., Baldwin, Stephen A., Waterham, Hans R., Theodoulou, Frederica L., Baker, Alison
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642094/
https://ncbi.nlm.nih.gov/pubmed/31324846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46685-9
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