Mutagenesis separates ATPase and thioesterase activities of the peroxisomal ABC transporter, Comatose

The peroxisomal ABC transporter, Comatose (CTS), a full length transporter from Arabidopsis has intrinsic acyl-CoA thioesterase (ACOT) activity, important for physiological function. We used molecular modelling, mutagenesis and biochemical analysis to identify amino acid residues important for ACOT...

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Publicat a:Sci Rep
Autors principals: Carrier, David J., van Roermund, Carlo W. T., Schaedler, Theresia A., Rong, Hong Lin, IJlst, Lodewijk, Wanders, Ronald J. A., Baldwin, Stephen A., Waterham, Hans R., Theodoulou, Frederica L., Baker, Alison
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642094/
https://ncbi.nlm.nih.gov/pubmed/31324846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46685-9
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