Mutagenesis separates ATPase and thioesterase activities of the peroxisomal ABC transporter, Comatose

The peroxisomal ABC transporter, Comatose (CTS), a full length transporter from Arabidopsis has intrinsic acyl-CoA thioesterase (ACOT) activity, important for physiological function. We used molecular modelling, mutagenesis and biochemical analysis to identify amino acid residues important for ACOT...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Carrier, David J., van Roermund, Carlo W. T., Schaedler, Theresia A., Rong, Hong Lin, IJlst, Lodewijk, Wanders, Ronald J. A., Baldwin, Stephen A., Waterham, Hans R., Theodoulou, Frederica L., Baker, Alison
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642094/
https://ncbi.nlm.nih.gov/pubmed/31324846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46685-9
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