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Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
The C-terminus of α-tubulin undergoes a detyrosination/tyrosination cycle and dysregulation of this cycle is associated with cancer and other diseases. The molecular mechanisms of tubulin tyrosination are well studied, however it has remained unknown how tyrosine is cleaved from the tubulin tail. He...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642083/ https://ncbi.nlm.nih.gov/pubmed/31324789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11277-8 |
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