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Ferrochelatase Deficiency Abrogated the Enhancement of Aminolevulinic Acid-mediated Protoporphyrin IX by Iron Chelator Deferoxamine

Aminolevulinic acid (ALA) is a prodrug that is metabolized in the heme biosynthesis pathway to produce protoporphyrin IX (PpIX) for tumor fluorescence detection and photodynamic therapy (PDT). The iron chelator deferoxamine (DFO) has been widely used to enhance PpIX accumulation by inhibiting the ir...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Photochem Photobiol
Prif Awduron: Palasuberniam, Pratheeba, Kraus, Daniel, Mansi, Matthew, Braun, Alexander, Howley, Richard, Myers, Kenneth A., Chen, Bin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642023/
https://ncbi.nlm.nih.gov/pubmed/30767226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.13091
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