Chronic hepatitis delta virus infection leads to functional impairment and severe loss of MAIT cells

BACKGROUND & AIMS: Hepatitis delta virus (HDV) infection is the most severe form of viral hepatitis. Although HDV-associated liver disease is considered immune-mediated, adaptive immune responses against HDV are weak. Thus, the role of several other cell-mediated mechanisms such as those driven...

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Veröffentlicht in:J Hepatol
Hauptverfasser: Dias, Joana, Hengst, Julia, Parrot, Tiphaine, Leeansyah, Edwin, Lunemann, Sebastian, Malone, David F.G., Hardtke, Svenja, Strauss, Otto, Zimmer, Christine L., Berglin, Lena, Schirdewahn, Thomas, Ciesek, Sandra, Marquardt, Nicole, von Hahn, Thomas, Manns, Michael P., Cornberg, Markus, Ljunggren, Hans-Gustaf, Wedemeyer, Heiner, Sandberg, Johan K., Björkström, Niklas K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642010/
https://ncbi.nlm.nih.gov/pubmed/31100314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.04.009
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