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Theoretical Study on the Epimerization of Azlactone Rings: Keto–Enol Tautomerism or Base-Mediated Racemization?

[Image: see text] Azlactones are versatile heterocycles employed in a diversity of transformations; the main drawback of these cycles consists in the epimerization of the α-carbonyl stereocenter during its preparation. We hereby present a theoretical study to explain how the racemization occurs. Two...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Omega
Egile Nagusiak: de Castro, Pedro P., Batista, Gabriel M. F., dos Santos, Hélio F., Amarante, Giovanni W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2018
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641619/
https://ncbi.nlm.nih.gov/pubmed/31458601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00060
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