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Ene Reactions of Nitrosocarbonyl Intermediates with Trisubstituted Cycloalkenes: “Cis Effect” and Steric and Conformational Factors Drive the Selectivity

[Image: see text] Nitrosocarbonyl intermediates, generated at room temperature by oxidation of nitrile oxides, undergo clean ene reactions with trisubstituted cycloalkenes. Nitrosocarbonyl benzene follows a Markovnikov orientation and abstracts preferentially the twix hydrogens over the lone ones. W...

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Dettagli Bibliografici
Pubblicato in:ACS Omega
Autori principali: Memeo, Misal Giuseppe, Re, Claudio, Aimone, Francesco, Quadrelli, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641422/
https://ncbi.nlm.nih.gov/pubmed/31457923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01124
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