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Hydrohalogenation of Ethynylpyridines Involving Nucleophilic Attack of a Halide Ion
[Image: see text] Efficient hydrochlorination of 2-ethynylpyridines was achieved without the use of special reagents. Ethynylpyridine readily reacts with hydrochloric acid to form a pyridinium salt. The salt formation considerably enhances the electrophilicity of the ethynyl group and attracts a chl...
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| Pubblicato in: | ACS Omega |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2017
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640932/ https://ncbi.nlm.nih.gov/pubmed/31457502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00133 |
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