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Applicability of Traditional In Vitro Toxicity Tests for Assessing Adverse Effects of Monoclonal Antibodies: A Case Study of Rituximab and Trastuzumab

Monoclonal antibody (mAb) therapeutics have a promising outlook within the pharmaceutical industry having made positive strides in both research and development as well as commercialisation, however this development has been hampered by manufacturing failures and attrition. This study explores the a...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Kizhedath, Arathi, Wilkinson, Simon, Glassey, Jarka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640679/
https://ncbi.nlm.nih.gov/pubmed/31544882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib7030030
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