Discovery of All Three Types in Cartilaginous Fishes Enables Phylogenetic Resolution of the Origins and Evolution of Interferons

Interferons orchestrate host antiviral responses in jawed vertebrates. They are categorized into three classes; IFN1 and IFN3 are the primary antiviral cytokine lineages, while IFN2 responds to a broader variety of pathogens. The evolutionary relationships within and between these three classes have...

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發表在:Front Immunol
Main Authors: Redmond, Anthony K., Zou, Jun, Secombes, Christopher J., Macqueen, Daniel J., Dooley, Helen
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640115/
https://ncbi.nlm.nih.gov/pubmed/31354716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01558
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