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Palladium-Catalyzed Dearomative syn-1,4-Carboamination with Grignard Reagents

A protocol for palladium-catalyzed dearomative functionalization of simple, non-activated arenes with Grignard reagents has been established. This one-pot method features a visible-light-mediated [4+2] cycloaddition between an arene and an arenophile, and subsequent palladium-catalyzed allylic subst...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Tang, Conghui, Okumura, Mikiko, Zhu, Yunbo, Hooper, Annie R., Zhou, Yu, Lee, Yu-Hsuan, Sarlah, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640109/
https://ncbi.nlm.nih.gov/pubmed/31090252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201905021
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