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The Mitochondrial Heme Metabolon: Insights into the Complex(ity) of Heme Synthesis and Distribution

Heme is an essential cofactor in metazoans that is also toxic in its free state. Heme is synthesized by most metazoans and must be delivered to all cellular compartments for incorporation into a variety of hemoproteins. The heme biosynthesis enzymes have been proposed to exist in a metabolon, a prot...

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Detalles Bibliográficos
Publicado en:Mol Genet Metab
Main Authors: Piel, Robert B., Dailey, Harry A., Medlock, Amy E.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640082/
https://ncbi.nlm.nih.gov/pubmed/30709775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.01.006
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