Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

Efficient migration of macrophages to sites of inflammation requires cell surface–bound plasmin(ogen). Here, we investigated the mechanisms underlying the deficits of plasmin(ogen)-mediated macrophage migration in 2 models: murine thioglycollate-induced peritonitis and in vitro macrophage migration....

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Silva, Lakmali Munasinghage, Lum, Andrew Gary, Tran, Collin, Shaw, Molly W., Gao, Zhen, Flick, Matthew J., Moutsopoulos, Niki M., Bugge, Thomas H., Mullins, Eric S.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Thrombosis and Hemostasis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639982/
https://ncbi.nlm.nih.gov/pubmed/31101623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018874859
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