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FBN1: The Disease-Causing Gene for Marfan Syndrome and Other Genetic Disorders
FBN1 encodes the gene for fibrillin-1, a structural macromolecule that polymerizes into microfibrils. Fibrillin microfibrils are morphologically distinctive fibrils, present in all connective tissues and assembled into tissue-specific architectural frameworks. FBN1 is the causative gene for Marfan s...
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| Publicado no: | Gene |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6639799/ https://ncbi.nlm.nih.gov/pubmed/27437668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.07.033 |
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