A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice

Neutrophil infiltration plays a significant pathological role in inflammatory diseases. NADPH oxidase type 2 (NOX2) is a respiratory burst oxidase that generates large amounts of superoxide anion (O(2)(•−)) and subsequent other reactive oxygen species (ROS). NOX2 is an emerging therapeutic target fo...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Liu, Fu-Chao, Yu, Huang-Ping, Chen, Po-Jen, Yang, Hsuan-Wu, Chang, Shih-Hsin, Tzeng, Cherng-Chyi, Cheng, Wei-Jen, Chen, You-Ren, Chen, Yeh-Long, Hwang, Tsong-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639650/
https://ncbi.nlm.nih.gov/pubmed/31325723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101273
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