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Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis

BACKGROUND: DNA methylation, acknowledged as a key modification in the field of epigenetics, regulates gene expression at the transcriptional level. Aberrant methylation in DNA regulatory regions could upregulate oncogenes and downregulate tumor suppressor genes without changing the sequences. Howev...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Liang, Yu, Zhang, Cheng, Dai, Dong-Qiu
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639549/
https://ncbi.nlm.nih.gov/pubmed/31341364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i26.3392
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