Paclitaxel-Loaded Nanosponges Inhibit Growth and Angiogenesis in Melanoma Cell Models

This study investigated the effects of free paclitaxel (PTX) and PTX-loaded in pyromellitic nanosponges (PTX-PNS) in reducing in vitro and in vivo melanoma cell growth and invasivity, and in inhibiting angiogenesis. To test the response of cells to the two PTX formulations, the cell viability was ev...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Clemente, Nausicaa, Argenziano, Monica, Gigliotti, Casimiro Luca, Ferrara, Benedetta, Boggio, Elena, Chiocchetti, Annalisa, Caldera, Fabrizio, Trotta, Francesco, Benetti, Elisa, Annaratone, Laura, Ribero, Simone, Pizzimenti, Stefania, Barrera, Giuseppina, Dianzani, Umberto, Cavalli, Roberta, Dianzani, Chiara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639435/
https://ncbi.nlm.nih.gov/pubmed/31354491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00776
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