Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

mRNA transport restricts translation to specific subcellular locations, which is the basis for many cellular functions. However, the precise process of mRNA sorting to synapses in neurons remains elusive. Here we use Rgs4 mRNA to investigate 3′-UTR-dependent transport by MS2 live-cell imaging. The m...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bauer, Karl E., Segura, Inmaculada, Gaspar, Imre, Scheuss, Volker, Illig, Christin, Ammer, Georg, Hutten, Saskia, Basyuk, Eugénia, Fernández-Moya, Sandra M., Ehses, Janina, Bertrand, Edouard, Kiebler, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639396/
https://ncbi.nlm.nih.gov/pubmed/31320644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11123-x
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