Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells

Formation of new blood vessels by differentiated endothelial tip cells, stalk cells, and phalanx cells during angiogenesis is an energy-demanding process. How these specialized endothelial cell phenotypes generate their energy, and whether there are differences between these phenotypes, is unknown....

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yetkin-Arik, B., Vogels, I. M. C., Neyazi, N., van Duinen, V., Houtkooper, R. H., van Noorden, C. J. F., Klaassen, I., Schlingemann, R. O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639367/
https://ncbi.nlm.nih.gov/pubmed/31320669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46503-2
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