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Interleukin-12 and -23 blockade mitigates elastase-induced abdominal aortic aneurysm

Macrophages play an important role in the inflammatory process that contributes to the development of abdominal aortic aneurysm (AAA). Studies of human and mouse AAA tissue reveal expanded populations of macrophages producing an abundance of pro-inflammatory cytokines, including TNF-α, IL-12p40 and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Huimin, Hu, Ying, Akk, Antonina, Ye, Karen, Bacon, John, Pham, Christine T. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639297/
https://ncbi.nlm.nih.gov/pubmed/31320700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46909-y
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