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The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes

Baculoviruses, although they infect insects in nature, can transduce a wide variety of mammalian cells and are therefore promising gene therapy vectors. However, baculovirus transduction into many mammalian cells is very inefficient, and the limiting stages and factors remain unknown. An important f...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Hu, Liangbo, Li, Yimeng, Ning, Yun-Jia, Deng, Fei, Vlak, Just M., Hu, Zhihong, Wang, Hualin, Wang, Manli
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639295/
https://ncbi.nlm.nih.gov/pubmed/31092570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-19
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