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The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes

Baculoviruses, although they infect insects in nature, can transduce a wide variety of mammalian cells and are therefore promising gene therapy vectors. However, baculovirus transduction into many mammalian cells is very inefficient, and the limiting stages and factors remain unknown. An important f...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Hu, Liangbo, Li, Yimeng, Ning, Yun-Jia, Deng, Fei, Vlak, Just M., Hu, Zhihong, Wang, Hualin, Wang, Manli
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639295/
https://ncbi.nlm.nih.gov/pubmed/31092570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-19
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