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The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes

Baculoviruses, although they infect insects in nature, can transduce a wide variety of mammalian cells and are therefore promising gene therapy vectors. However, baculovirus transduction into many mammalian cells is very inefficient, and the limiting stages and factors remain unknown. An important f...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Hu, Liangbo, Li, Yimeng, Ning, Yun-Jia, Deng, Fei, Vlak, Just M., Hu, Zhihong, Wang, Hualin, Wang, Manli
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639295/
https://ncbi.nlm.nih.gov/pubmed/31092570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-19
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