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Modeling the Dynamics of Let-7-Coupled Gene Regulatory Networks Linking Cell Proliferation to Malignant Transformation

Let-7 microRNA controls the expression of proteins that belong to two distinct gene regulatory networks, namely, a cyclin-dependent kinase (Cdk) network driving the cell cycle and a cell transformation network that can undergo an epigenetic switch between a non-transformed and a malignant transforme...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Gérard, Claude, Lemaigre, Frédéric, Gonze, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637753/
https://ncbi.nlm.nih.gov/pubmed/31354514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00848
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