Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice

Syncytin-A and -B are envelope genes of retroviral origin that have been captured in evolution for a role in placentation. They trigger cell-cell fusion and were shown to be essential for the formation of the syncytiotrophoblast layer during mouse placenta formation. Syncytin-A and -B expression has...

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Vydáno v:Bone Rep
Hlavní autoři: Coudert, Amélie E., Redelsperger, François, Chabbi-Achengli, Yasmine, Vernochet, Cécile, Marty, Caroline, Decrouy, Xavier, Heidmann, Thierry, de Vernejoul, Marie-Christine, Dupressoir, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637224/
https://ncbi.nlm.nih.gov/pubmed/31360740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2019.100214
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