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Establishment and equilibrium levels of deleterious mutations in large populations
Analytical and statistical stochastic approaches are used to model the dispersion of monogenic variants through large populations. These approaches are used to quantify the magnitude of the selective advantage of a monogenic heterozygous variant in the presence of a homozygous disadvantage. Dunbar’s...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6637196/ https://ncbi.nlm.nih.gov/pubmed/31316137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46803-7 |
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