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Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro
Notch signaling has been shown to regulate the homeostasis and wound healing of the corneal epithelium. We investigated the effect of Notch inhibition in the human limbal stem/progenitor cells (LSCs) in vitro by using small molecules. Treatment of the LSCs with DAPT and SAHM1 reduced the proliferati...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6637172/ https://ncbi.nlm.nih.gov/pubmed/31316119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46793-6 |
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