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Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro

Notch signaling has been shown to regulate the homeostasis and wound healing of the corneal epithelium. We investigated the effect of Notch inhibition in the human limbal stem/progenitor cells (LSCs) in vitro by using small molecules. Treatment of the LSCs with DAPT and SAHM1 reduced the proliferati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: González, Sheyla, Uhm, Heui, Deng, Sophie X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637172/
https://ncbi.nlm.nih.gov/pubmed/31316119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46793-6
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