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Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing

Whole genome bisulfite sequencing (WGBS), with its ability to interrogate methylation status at single CpG site resolution epigenome-wide, is a powerful technique for use in molecular experiments. Here, we aim to advance strategies for accurate and efficient WGBS for application in future large-scal...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Li, Ng, Hong Kiat, Drautz-Moses, Daniela I., Schuster, Stephan C., Beck, Stephan, Kim, Changhoon, Chambers, John Campbell, Loh, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637168/
https://ncbi.nlm.nih.gov/pubmed/31316107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46875-5
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