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Dysfunctional EAT thickness may promote maladaptive heart remodeling in CVD patients through the ST2-IL33 system, directly related to EPAC protein expression

Dysfunctional epicardial adipose tissue (EAT) secretome can influence the heart’s stretch response. However, the molecular mechanisms are still poorly understood. The aim of this study was to clarify how dysfunctional EAT promotes maladaptive heart remodeling in cardiovascular disease (CVD) through...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Vianello, Elena, Dozio, Elena, Bandera, Francesco, Schmitz, Gerd, Nebuloni, Manuela, Longhi, Erika, Tacchini, Lorenza, Guazzi, Marco, Corsi Romanelli, Massimiliano Marco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637132/
https://ncbi.nlm.nih.gov/pubmed/31316160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46676-w
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