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Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase

Albeit osteoporosis is one of the most prevalent disorders in the aged population, treatment options stimulating the activity of bone-forming osteoblasts are still limited. We and others have previously identified sphingosine-1-phosphate (S1P) as a bone remodeling coupling factor, which is released...

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Publicado en:PLoS One
Autores principales: Heckt, Timo, Brylka, Laura J., Neven, Mona, Amling, Michael, Schinke, Thorsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636735/
https://ncbi.nlm.nih.gov/pubmed/31314788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219734
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