Orally delivered resveratrol-loaded lipid-core nanocapsules ameliorate LPS-induced acute lung injury via the ERK and PI3K/Akt pathways

BACKGROUND: Resveratrol (RSV) has attracted interest as an alternative drug for the treatment of acute lung injury (ALI) and other pulmonary diseases, but its poor oral bioavailability is a limitation. In this study, we employed drug delivery nanotechnology to improve the stability, lung localizatio...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: de Oliveira, Maria Talita Pacheco, de Sá Coutinho, Diego, Tenório de Souza, Éverton, Stanisçuaski Guterres, Sílvia, Pohlmann, Adriana Raffin, Silva, Patricia Machado Rodrigues, Martins, Marco Aurélio, Bernardi, Andressa
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636190/
https://ncbi.nlm.nih.gov/pubmed/31371957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S200666
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