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Protein Kinase C Lambda Mediates Acid-Sensing Ion Channel 1a-Dependent Cortical Synaptic Plasticity and Pain Hypersensitivity

Chronic pain is a serious debilitating disease for which effective treatment is still lacking. Acid-sensing ion channel 1a (ASIC1a) has been implicated in nociceptive processing at both peripheral and spinal neurons. However, whether ASIC1a also contributes to pain perception at the supraspinal leve...

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Vydáno v:J Neurosci
Hlavní autoři: Li, Hu-Song, Su, Xin-Yu, Song, Xing-Lei, Qi, Xin, Li, Ying, Wang, Rui-Qi, Maximyuk, Oleksandr, Krishtal, Oleg, Wang, Tingting, Fang, Houqin, Liao, Lujian, Cao, Hong, Zhang, Yu-Qiu, Zhu, Michael X., Liu, Ming-Gang, Xu, Tian-Le
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636072/
https://ncbi.nlm.nih.gov/pubmed/31101759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0213-19.2019
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