Causes and Effects of Loss of Classical Nonhomologous End Joining Pathway in Parasitic Eukaryotes

We report frequent losses of components of the classical nonhomologous end joining pathway (C-NHEJ), one of the main eukaryotic tools for end joining repair of DNA double-strand breaks, in several lineages of parasitic protists. Moreover, we have identified a single lineage among trypanosomatid flag...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:mBio
Egile Nagusiak: Nenarokova, Anna, Záhonová, Kristína, Krasilnikova, Marija, Gahura, Ondřej, McCulloch, Richard, Zíková, Alena, Yurchenko, Vyacheslav, Lukeš, Julius
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Observation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635534/
https://ncbi.nlm.nih.gov/pubmed/31311886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01541-19
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