Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness

Cholesterol mediates its proliferative and metastatic effects via the metabolite 27-hydroxycholesterol (27-HC), at least in breast and endometrial cancer. We determined the serum lipoprotein profile, intratumoral cholesterol and 27-HC levels in a cohort of patients with well-differentiated papillary...

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Vydáno v:Sci Rep
Hlavní autoři: Revilla, Giovanna, Pons, Monica de Pablo, Baila-Rueda, Lucía, García-León, Annabel, Santos, David, Cenarro, Ana, Magalhaes, Marcelo, Blanco, R. M., Moral, Antonio, Ignacio Pérez, José, Sabé, Gerard, González, Cintia, Fuste, Victoria, Lerma, Enrique, Faria, Manuel dos Santos, de Leiva, Alberto, Corcoy, Rosa, Carles Escolà-Gil, Joan, Mato, Eugenia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635382/
https://ncbi.nlm.nih.gov/pubmed/31311983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46727-2
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