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Leveraging the genetic basis of Rett syndrome to ascertain pathophysiology

Mutations in the methyl-CpG binding protein 2 (MECP2) gene cause Rett syndrome (RTT), a progressive X-linked neurological disorder characterized by loss of developmental milestones, intellectual disability and breathing abnormality. Despite being a monogenic disorder, the pathogenic mechanisms by wh...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Learn Mem
Asıl Yazarlar: Yang, Hua, Li, Kequan, Han, Song, Zhou, Ailing, Zhou, Zhaolan (Joe)
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635128/
https://ncbi.nlm.nih.gov/pubmed/30447288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2018.11.006
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