Down-regulation of human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation

PURPOSE: Renal cell carcinoma (RCC) is known to be highly radio-resistant but the mechanisms associated with radio-resistance have remained elusive. We found DAB2IP frequently down-regulated in RCC, is associated with radio-resistance. In this study, we investigated the underlying mechanism regulati...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Yun, Eun-Jin, Lin, Chun-Jung, Dang, Andrew, Hernandez, Elizabeth, Guo, Jiaming, Chen, Wei-Min, Allison, Joyce, Kim, Nathan, Kapur, Payal, Brugarolas, James, Wu, Kaijie, He, Dalin, Lai, Chih-Ho, Lin, Ho, Saha, Debabrata, Baek, Seung Tae, Chen, Benjamin P.C., Hsieh, Jer-Tsong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635020/
https://ncbi.nlm.nih.gov/pubmed/31000589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3004
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