Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Dissecting the pathogenesis of classical Hodgkin lymphoma (cHL), a common cancer in young adults, remains challenging because of the rarity of tumor cells in involved tissues (usually <5%). Here, we analyzed the coding genome of cHL by microdissecting tumor and normal cells from 34 patient biopsi...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Tiacci, Enrico, Ladewig, Erik, Schiavoni, Gianluca, Penson, Alex, Fortini, Elisabetta, Pettirossi, Valentina, Wang, Yuchun, Rosseto, Ariele, Venanzi, Alessandra, Vlasevska, Sofija, Pacini, Roberta, Piattoni, Simonetta, Tabarrini, Alessia, Pucciarini, Alessandra, Bigerna, Barbara, Santi, Alessia, Gianni, Alessandro M., Viviani, Simonetta, Cabras, Antonello, Ascani, Stefano, Crescenzi, Barbara, Mecucci, Cristina, Pasqualucci, Laura, Rabadan, Raul, Falini, Brunangelo
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2018
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634958/
https://ncbi.nlm.nih.gov/pubmed/29650799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-11-814913
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