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PKA-Induced Internalization of Slack K(Na) Channels Produces Dorsal Root Ganglion Neuron Hyperexcitability

Inflammatory mediators through the activation of the protein kinase A (PKA) pathway sensitize primary afferent nociceptors to mechanical, thermal, and osmotic stimuli. However, it is unclear which ion conductances are responsible for PKA-induced nociceptor hyperexcitability. We have previously shown...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Nuwer, Megan O., Picchione, Kelly E., Bhattacharjee, Arin
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634761/
https://ncbi.nlm.nih.gov/pubmed/20962237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3150-10.2010
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