Quantitative Analysis of Synaptic Vesicle Rabs Uncovers Distinct Yet Overlapping Roles for Rab3a and Rab27b in Ca(2+)-Triggered Exocytosis

Rab GTPases are molecular switches that orchestrate protein complexes before membrane fusion reactions. In synapses, Rab3 and Rab5 proteins have been implicated in the exo-endocytic cycling of synaptic vesicles (SVs), but an involvement of additional Rabs cannot be excluded. Here, combining high-res...

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Udgivet i:J Neurosci
Main Authors: Pavlos, Nathan J., Grønborg, Mads, Riedel, Dietmar, Chua, John J. E., Boyken, Janina, Kloepper, Tobias H., Urlaub, Henning, Rizzoli, Silvio O., Jahn, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634719/
https://ncbi.nlm.nih.gov/pubmed/20926670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0907-10.2010
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