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CD47 Blockade and Cowpea Mosaic Virus Nanoparticle in situ Vaccination Synergistically Triggers Phagocytosis and Tumor Killing

Contemporary immunotherapies, e.g. those that target the CTLA-4 and PD-1/PD-L1 axis, act on T cells to reinstate their antitumor activity. An alternative, and possibly more powerful approach is to target and reprogram the innate immune system within the tumor microenvironment. To this end, blockade...

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Publicat a:Adv Healthc Mater
Autors principals: Wang, Chao., Steinmetz, Nicole. F.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633909/
https://ncbi.nlm.nih.gov/pubmed/30838815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201801288
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