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The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking

The niche controls stem cell self-renewal and differentiation in animal tissues. Although the exocyst is known to be important for protein membrane trafficking and secretion, its role in stem cells and niches has never been reported. Here, this study shows that the exocyst functions in the niche to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Mao, Ying, Tu, Renjun, Huang, Yan, Mao, Decai, Yang, Zhihao, Lau, Pik Ki, Wang, Jinhui, Ni, Jianquan, Guo, Yusong, Xie, Ting
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633608/
https://ncbi.nlm.nih.gov/pubmed/31142545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.174615
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