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A trap mutant reveals the physiological client spectrum of TRC40

The transmembrane recognition complex (TRC) pathway targets tail-anchored (TA) proteins to the membrane of the endoplasmic reticulum (ER). While many TA proteins are known to be able to use this pathway, it is essential for the targeting of only a few. Here, we uncover a large number of TA proteins...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Coy-Vergara, Javier, Rivera-Monroy, Jhon, Urlaub, Henning, Lenz, Christof, Schwappach, Blanche
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633398/
https://ncbi.nlm.nih.gov/pubmed/31182645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230094
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