Deletion of ERK1 and ERK2 in the CNS Causes Cortical Abnormalities and Neonatal Lethality: Erk1 Deficiency Enhances the Impairment of Neurogenesis in Erk2-Deficient Mice

Intracellular signaling through extracellular signal-regulated kinase (ERK) is important in regulating cellular functions in a variety of tissues including the CNS. Although ERK1 and ERK2 have a very similar substrate profile and amino acid sequences, there are strikingly different phenotypes betwee...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Satoh, Yasushi, Kobayashi, Yasushi, Takeuchi, Atsuya, Pagès, Gilles, Pouysségur, Jacques, Kazama, Tomiei
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632941/
https://ncbi.nlm.nih.gov/pubmed/21248139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2243-10.2011
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