12-Lipoxygenase promotes epithelial–mesenchymal transition via the Wnt/β-catenin signaling pathway in gastric cancer cells

BACKGROUND: 12-Lipoxygenase (12-LOX) plays a major role in the progression and metastasis of various types of cancer. In gastric cancer (GC), the expression level of 12-LOX is significantly up-regulated; however, its function, and underlying mechanism of action remain unclear. METHODS: The mRNA and...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Yang, Xiao-Huang, Zhuang, Ming-Kai, Xie, Wen-Hui, Du, Fan, Huang, Yue-Hong, Chen, Zhi-Xin, Chen, Feng-Lin, Wang, Xiao-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632671/
https://ncbi.nlm.nih.gov/pubmed/31371993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S201373
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