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Pharmacological and Genetic Accumulation of Hypoxia-Inducible Factor-1α Enhances Excitatory Synaptic Transmission in Hippocampal Neurons through the Production of Vascular Endothelial Growth Factor
Hypoxia-inducible factor-1 (HIF-1) is an important transcriptional factor in mammalian cells for coordination of adaptive responses to hypoxia. It consists of a regulatory subunit HIF-1α, which accumulates under hypoxic conditions, and a constitutively expressed subunit HIF-1β. In addition to the we...
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| Published in: | J Neurosci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632593/ https://ncbi.nlm.nih.gov/pubmed/20427666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5493-09.2010 |
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