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Pharmacological and Genetic Accumulation of Hypoxia-Inducible Factor-1α Enhances Excitatory Synaptic Transmission in Hippocampal Neurons through the Production of Vascular Endothelial Growth Factor

Hypoxia-inducible factor-1 (HIF-1) is an important transcriptional factor in mammalian cells for coordination of adaptive responses to hypoxia. It consists of a regulatory subunit HIF-1α, which accumulates under hypoxic conditions, and a constitutively expressed subunit HIF-1β. In addition to the we...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Huang, Yu-Fei, Yang, Chih-Hao, Huang, Chiung-Chun, Tai, Ming-Hong, Hsu, Kuei-Sen
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632593/
https://ncbi.nlm.nih.gov/pubmed/20427666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5493-09.2010
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